News for Healthier Living

'Deaths of Despair' More than Double in the U.S. Over Two Decades

A study finds a troubling rise in 'deaths of despair' in the U.S. from 1999 to 2021, using the International Classification of Diseases. These deaths, defined by 19 underlying causes such as chronic hepatitis, liver cirrhosis, suicide, drug overdoses, and alcohol-related conditions, increased two-and-a-half-fold over two decades. By 2021, deaths of despair would have become the fifth leading cause of death in the U.S., surpassing 176,000 fatalities, and ranking just behind heart disease, cancer, COVID-19 and accidents.

February 20, 2025


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