News for Healthier Living

Choline Supplementation in Young Children with Fetal Alcohol Spectrum Disorder Has Durable Developmental Benefits, with Gains Evident Five Years Later, Study Suggests

Children impacted by prenatal alcohol exposure (PAE) experience long-lasting cognitive gains after treatment with supplemental choline, an essential nutrient, a new study suggests. The findings point to a potentially scalable intervention for neurodevelopmental differences that currently have few treatment options. Fetal Alcohol Spectrum Disorder (FASD) is an umbrella term for several diagnoses, affecting 1-5% of the global population, that can involve physical, cognitive, and behavioral deficits and challenges. Choline supplementation has been shown to positively impact brain development in animal models of PAE. Prenatal choline supplementation during human pregnancies involving alcohol exposure has also shown benefits. While randomized controlled trials (RCTs) of FASD treatments have been scarce, researchers at the University of Minnesota previously conducted three such studies involving choline supplementation in young children. For the new study in Alcohol: Clinical & Experimental

October 12, 2026


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