News for Healthier Living

Deficits in a Mouse Model of Autism-Related Neurodevelopmental Disorder and Discover that Early-Life Exercise Intervention Can Improve Motor Outcomes

Using a mouse model of a neurodevelopmental disorder and genetic form of autism called DDX3X syndrome, the researchers discovered that the motor deficits characteristic of the syndrome depend on a specific brain circuit that connects the cortex with a particular nucleus in the brainstem. The researchers also found that an early intervention can improve motor trajectories, providing insights on the plasticity of the underlying circuits and their potential for therapeutic targeting.

October 26, 2026


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