Pronunciation: eye SOCK soo prin

Brand: Vasodilan

What is the most important information I should know about isoxsuprine?

Use caution when driving, operating machinery, or performing other hazardous activities. Isoxuprine may cause dizziness. If you experience dizziness, avoid these activities. Also, rise slowly from a sitting or lying position to avoid falling.

Notify your doctor if you experience a rash or bothersome irregular heartbeats.

Isoxsuprine has been withdrawn from the U.S. market.

What is isoxsuprine?

Isoxsuprine is in a class of drugs called vasodilators. Isoxsuprine relaxes veins and arteries, which makes them wider and allows blood to pass through them more easily.

These actions may help treat the symptoms of conditions such as cerebral vascular insufficiency (poor blood flow to the brain), arteriosclerosis (hardening of the arteries), Raynaud's phenomenon, and other conditions involving poor blood flow in the veins and arteries.

Isoxsuprine may also be used for purposes other than those listed in this medication guide.

What should I discuss with my healthcare provider before taking isoxsuprine?

Isoxsuprine should not be used immediately postpartum (after delivering a baby), or if you have a bleeding disorder. Talk to your doctor about any other medical conditions that you have.

Isoxsuprine is in the FDA pregnancy category C. This means that it is not known whether isoxsuprine will be harmful to an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant or could become pregnant during treatment.

It is not known whether isoxsuprine passes into breast milk. Do not take this medication without first talking to your doctor if you are breast-feeding a baby.

How should I take isoxsuprine?

Take isoxsuprine exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water.

Isoxsuprine is usually taken three or four times a day. Follow your doctor's instructions.

It is important to take isoxsuprine regularly to get the most benefit.

Your doctor may want you to have blood tests or other medical evaluations during treatment with isoxsuprine to monitor progress and side effects.

Store isoxsuprine at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication.

What happens if I overdose?

Seek emergency medical attention if an overdose is suspected.

Symptoms of an isoxsuprine overdose include weakness, lightheadedness, fainting, nausea, and vomiting.

What should I avoid while taking isoxsuprine?

Use caution when driving, operating machinery, or performing other hazardous activities. Isoxsuprine may cause dizziness. If you experience dizziness, avoid these activities. Also, rise slowly from a sitting or lying position to avoid falling.

What are the possible side effects of isoxsuprine?

Stop taking isoxsuprine and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives).

Stop taking isoxsuprine and contact your doctor if you develop a rash.

Other, less serious side effects may be more likely to occur. Continue to take isoxsuprine and talk to your doctor if you experience

  • chest pain or an irregular heartbeat (call your doctor if this becomes bothersome);
  • nausea or vomiting; or
  • dizziness or weakness.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect isoxsuprine?

Drugs used to treat high blood pressure and other heart conditions may increase the effects of isoxsuprine. Special monitoring may be necessary.

Drugs other than those listed here may also interact with isoxsuprine or affect your condition. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

Where can I get more information?

Your pharmacist has additional information about isoxsuprine written for health professionals that you may read.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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