buprenorphine (oral/sublingual)
buprenorphine (oral/sublingual)Skip to the navigationWhat is the most important information I should know about buprenorphine sublingual?Buprenorphine sublingual tablets are not for use as a pain medication. Buprenorphine can slow or stop your breathing, and may be habit-forming. Use only your prescribed dose. Never share buprenorphine with another person. MISUSE OF NARCOTIC MEDICINE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH, especially in a child or other person using the medicine without a prescription. Tell your doctor if you are pregnant. Buprenorphine may cause life-threatening withdrawal symptoms in a newborn. What is buprenorphine sublingual?Buprenorphine is an opioid medication. An opioid is sometimes called a narcotic. Buprenorphine oral (sublingual, given under the tongue) is used to treat narcotic addiction. Buprenorphine sublingual tablets are not for use as a pain medication. Buprenorphine may also be used for purposes not listed in this medication guide. What should I discuss with my healthcare provider before taking buprenorphine sublingual?You should not use this medicine if you are allergic to buprenorphine, or: - if you have used another narcotic drug within the past 4 hours.
Some medicines can interact with buprenorphine and cause a serious condition called serotonin syndrome. Be sure your doctor knows if you also take medicine for depression, mental illness, Parkinson's disease, migraine headaches, serious infections, or prevention of nausea and vomiting. Ask your doctor before making any changes in how or when you take your medications. To make sure buprenorphine is safe for you, tell your doctor if you have: - any type of breathing problem or lung disease;
- abnormal curvature of the spine that affects breathing;
- liver disease (especially hepatitis B or C);
- kidney disease;
- enlarged prostate, urination problems;
- problems with your stomach, gallbladder, adrenal gland, or thyroid;
- a history of head injury or brain tumor;
- a history of alcohol addiction, hallucinations, or mental illness;
- a history of methadone use; or
- if you use a sedative like Valium (diazepam, alprazolam, lorazepam, Ativan, Klonopin, Restoril, Tranxene, Versed, Xanax, and others).
If you use buprenorphine while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks. Tell your doctor if you are pregnant or plan to become pregnant. Buprenorphine can pass into breast milk and may harm a nursing baby. You should not breast-feed while you are using buprenorphine. Buprenorphine is not approved for use by anyone younger than 18 years old. How should I take buprenorphine sublingual?Follow all directions on your prescription label. Buprenorphine can slow or stop your breathing. Never use buprenorphine in larger amounts, or for longer than prescribed. Buprenorphine sublingual is usually taken for only 1 or 2 days at the start of treatment for addiction. Most people are later switched to another medicine called buprenorphine/naloxone (Bunavail, Suboxone, Zubsolv). You may receive your first doses of buprenorphine sublingual in a hospital or clinic setting until your condition improves. Buprenorphine may be habit-forming, even at regular doses. Never share this medicine with another person, especially someone with a history of drug abuse or addiction. MISUSE OF NARCOTIC MEDICINE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH, especially in a child or other person using the medicine without a prescription. Selling or giving away buprenorphine is against the law. Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions. Use dry hands when handling the tablet. Place the tablet under your tongue and allow it to dissolve with your mouth closed. Do not chew the tablet or swallow it whole. If your doctor has prescribed more than 2 tablets per dose, place the correct number of tablets under your tongue at the same time and allow them to dissolve completely. Do not eat or drink anything until the tablet or film has completely dissolved in your mouth. While using buprenorphine, you may need frequent blood tests to check your liver function. If you need surgery, tell the surgeon ahead of time that you are using buprenorphine. You may need to stop using the medicine for a short time. Wear a medical alert tag or carry an ID card stating that you take buprenorphine. Any medical care provider who treats you should know that you are being treated for narcotic addiction. Make sure your family members know you are using buprenorphine in case they need to speak for you during an emergency. Do not stop using buprenorphine suddenly, or you could have unpleasant withdrawal symptoms. Ask your doctor how to safely stop using this medicine. Store at room temperature away from moisture and heat. Keep track of the amount of medicine used from each new bottle. Buprenorphine is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription. Do not keep leftover buprenorphine pills. Ask your pharmacist where to locate a drug take-back disposal program. If there is no take-back program, flush any unused pills down the toilet Never crush or break a buprenorphine pill or mix it into a liquid to inject the drug into your vein. This could result in a life-threatening infection or other serious medical problems. What happens if I miss a dose?Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose. What happens if I overdose?Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. A buprenorphine overdose can be fatal, especially in a child or other person using the medicine without a prescription. Overdose symptoms may include extreme drowsiness or weakness, cold or clammy skin, pinpoint pupils, fainting, slow heart rate, weak pulse, weak or shallow breathing (breathing may stop). What should I avoid while taking buprenorphine sublingual?Do not drink alcohol. Dangerous side effects or death could occur. Buprenorphine may impair your thinking or reactions. Avoid driving or operating machinery until you know how buprenorphine will affect you. Dizziness or severe drowsiness can cause falls or other accidents. What are the possible side effects of buprenorphine sublingual?Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Like other narcotic medicines, buprenorphine can slow your breathing. Death may occur if breathing becomes too weak. Call your doctor at once if you have: - chest pain, trouble breathing;
- weak or shallow breathing;
- a light-headed feeling, like you might pass out;
- severe dizziness, loss of coordination;
- confusion, unusual thoughts or behavior;
- infertility, missed menstrual periods;
- impotence, sexual problems, loss of interest in sex;
- opioid withdrawal symptoms --shivering, goose bumps, increased sweating, feeling hot or cold, runny nose, watery eyes, diarrhea, muscle pain;
- low cortisol levels -- nausea, vomiting, loss of appetite, dizziness, worsening tiredness or weakness; or
- liver problems --nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea. Common side effects may be more likely to occur, such as: - constipation, nausea, vomiting;
- headache;
- increased sweating;
- sleep problems (insomnia); or
- pain anywhere in your body.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. What other drugs will affect buprenorphine sublingual?Narcotic (opioid) medication can interact with many other drugs and cause dangerous side effects or death. Be sure your doctor knows if you also use: - other narcotic medications --opioid pain medicine or prescription cough medicine;
- drugs that make you sleepy or slow your breathing --a sleeping pill, muscle relaxer, sedative, tranquilizer, or antipsychotic medicine; or
- drugs that affect serotonin levels in your body --medicine for depression, Parkinson's disease, migraine headaches, serious infections, or prevention of nausea and vomiting.
This list is not complete. Other drugs may interact with buprenorphine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide. Where can I get more information?Your pharmacist can provide more information about buprenorphine sublingual.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist. Copyright 1996-2017 Cerner Multum, Inc. Version: 5.04. Revision date: 9/28/2016.
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Last modified on: 8 September 2017
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