methylphenidate (transdermal)

Skip to the navigation

Pronunciation: meth il FEN ih date

Brand: Daytrana

What is the most important information I should know about methylphenidate transdermal?

You should not use methylphenidate if you have glaucoma, tics or Tourette's syndrome, or severe anxiety, tension, or agitation. Do not use methylphenidate if you have taken an MAO inhibitor in the past 14 days, including isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

Methylphenidate may be habit forming. Never share this medicine with another person, especially someone with a history of drug abuse or addiction.

Using this medicine improperly can cause death or serious side effects on the heart.

What is methylphenidate transdermal?

Methylphenidate is a central nervous system stimulant. It affects chemicals in the brain and nerves that contribute to hyperactivity and impulse control.

Methylphenidate is used to treat attention deficit hyperactivity disorder (ADHD).

Methylphenidate may also be used for purposes not listed in this medication guide.

What should I discuss with my health care provider before using methylphenidate transdermal?

Do not use methylphenidate if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, and tranylcypromine.

You should not use this medicine if you are allergic to methylphenidate (Ritalin, Concerta, Metadate, and others), or if you have:

  • glaucoma;
  • a personal or family history of tics (muscle twitches) or Tourette's syndrome;
  • severe anxiety, tension, or agitation (stimulant medicine can make these symptoms worse); or
  • if you have ever had a skin reaction when using any type of adhesive bandage or transdermal skin patch.

Some stimulants have caused sudden death in certain people. Tell your doctor if you have:

  • heart problems or a congenital heart defect;
  • high blood pressure; or
  • a family history of heart disease or sudden death.

To make sure this medicine is safe for you, tell your doctor if you or anyone in your family has ever had:

  • a skin disorder (such as eczema, psoriasis), skin sensitivity to soaps, lotions, cosmetics, or glues;
  • depression, mental illness, bipolar disorder, psychosis, or suicidal thoughts or actions;
  • motor tics (muscle twitches) or Tourette's syndrome;
  • blood circulation problems in the hands or feet;
  • seizures or epilepsy, an abnormal brain wave test (EEG); or
  • a history of drug or alcohol addiction.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether methylphenidate passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Methylphenidate is not approved for use by anyone younger than 6 years old.

How should I use methylphenidate transdermal?

Follow all directions on your prescription label. Using this medicine improperly can cause death or serious side effects on the heart. Read all patient information, medication guides, and instruction sheets provided to you. The medicine comes with a dosing schedule that shows when to apply and remove a skin patch based on 9- hour time frames. Ask your doctor or pharmacist if you have any questions.

Methylphenidate may be habit-forming. Never share this medicine with another person, especially someone with a history of drug abuse or addiction. Selling or giving away this medicine is against the law.

Apply the patch to a clean and dry area on your hip. Press firmly onto the skin with the palm of your hand for about 30 seconds. The patch should stay on while swimming or bathing. The effects of this medicine may not be noticeable until 2 hours after applying the skin patch.

Wash your hands after applying a skin patch.

Remove the patch 9 hours after it was applied. Peel off slowly and fold the patch in half so it sticks together. Flush the folded patch down the toilet or place it into a waste can with a lid. If you discontinue using methylphenidate transdermal, fold together and flush any unused patches at that time.

Apply a new patch to the opposite hip. Do not wear a patch on the same side of the body two days in a row.

If a patch falls off, replace it with a new one. Then remove the new patch after it has been 9 hours since you applied the first patch. Do not wear a patch longer than 9 hours per day, even if you apply a new patch to replace one that has fallen off. Use the dosing schedule provided to track your patch wearing time.

Over time, methylphenidate transdermal can cause your skin to lighten around areas where the patches are worn. This effect may be permanent. Check your skin often. Tell your doctor if you see new areas of lighter color under or around a skin patch. Do not change your doses or medication schedule without your doctor's advice.

If you have trouble sleeping or loss of appetite in the evenings, try removing the skin patch earlier in the day. Never cut the skin patch to try and reduce the amount of medicine you receive while wearing it.

Children using this medicine should be warned never to remove the skin patch and place it onto another person. Serious side effects may result.

While using methylphenidate, your doctor will need to check your progress at regular visits. Your heart rate, blood pressure, height and weight may also need to be checked often.

Keep each patch in its sealed pouch until you are ready to use it. Store at room temperature away from heat and moisture. Do not refrigerate or freeze. Throw away any unused patches if it has been more than 2 months since you opened the original package.

Keep track of the amount of medicine used from each new package. Methylphenidate is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

What happens if I miss a dose?

Apply a patch as soon as you remember, and do not wear the patch for longer than 9 hours. You may need to shorten the wearing time to less than 9 hours if you apply a patch later than usual and you have sleep problems. Do not apply two patches at the same time to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Remove the patch right away and clean the skin area with soap and water. An overdose of methylphenidate can be fatal.

Overdose symptoms may include sweating, redness in your face, vomiting, shaking, confusion, agitation, hallucinations, and irregular heartbeat.

What should I avoid while using methylphenidate transdermal?

Do not expose the skin patch to heat while you are wearing it. This includes heat from a heating pad, hot tub, electric blanket, or a heated water bed. Heat can cause the skin patch to release too much medicine at one time.

Avoid placing a patch on skin that is oily, irritated, or damaged. Avoid a skin area that will be rubbed by a waistband or tight clothing.

This medication may cause blurred vision and can impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.

What are the possible side effects of methylphenidate transdermal?

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Methylphenidate can affect growth in children. Tell your doctor if your child is not growing at a normal rate while using this medicine.

Stop using methylphenidate and call your doctor at once if you have:

  • redness, swelling, blistering, or skin color changes where the skin patch was worn (may also spread to other areas);
  • chest pain, trouble breathing, feeling like you might pass out;
  • hallucinations (seeing or hearing things that are not real), new behavior problems, aggression, hostility, paranoia;
  • a seizure (convulsions);
  • numbness, pain, cold feeling, unexplained wounds, or skin color changes (pale, red, or blue appearance) in your fingers or toes;
  • muscle twitches (tics);
  • changes in your vision;
  • penis erection that is painful or lasts 4 hours or longer (rare); or
  • unexplained muscle pain, tenderness, or weakness (especially if you also have fever, unusual tiredness, and dark colored urine).

Common side effects may include:

  • dizziness, mood swings;
  • tics;
  • nausea, vomiting, stomach pain, loss of appetite, weight loss;
  • sleep problems (insomnia); or
  • mild skin redness, bumps, or itching where a patch was worn.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect methylphenidate transdermal?

Tell your doctor about all your current medicines and any you start or stop using, especially:

  • an antidepressant;
  • blood pressure medication;
  • a blood thinner such as warfarin (Coumadin, Jantoven);
  • a cold or allergy medicine that contains a decongestant such as pseudoephedrine or phenylephrine; or
  • seizure medicine.

This list is not complete. Other drugs may interact with methylphenidate, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

Where can I get more information?

Your pharmacist can provide more information about methylphenidate transdermal.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2017 Cerner Multum, Inc. Version: 6.02. Revision date: 7/6/2015.

Your use of the content provided in this service indicates that you have read, understood and agree to the End-User License Agreement, which can be accessed by clicking on this link.