deoxycholic acid

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Pronunciation: dee OX i KOE lik AS id

Brand: Kybella

What is the most important information I should know about deoxycholic acid?

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

What is deoxycholic acid?

Deoxycholic acid is a manmade form of a substance your body makes that helps to absorb fats. Deoxycholic acid works by destroying fat cells where it is injected into the body.

Deoxycholic acid is used to help decrease the appearance of fat that hangs below the chin, sometimes called a double-chin.

Deoxycholic acid has not been tested for safe use on other areas of the body.

Deoxycholic acid may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before receiving deoxycholic acid?

You should not use deoxycholic acid if you are allergic to it, or if you have:

  • an infection in or around the area to be treated.

To make sure deoxycholic acid is safe for you, tell your doctor if you have:

  • a history of surgery or other cosmetic treatments on your neck, chin, or face (or if you plan to have surgery on any of these areas);
  • trouble swallowing;
  • a thyroid disorder;
  • swollen lymph glands in your neck; or
  • a bleeding or blood clotting disorder such as hemophilia.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether deoxycholic acid passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Deoxycholic acid is not approved for use by anyone younger than 18 years old.

How is deoxycholic acid given?

Deoxycholic acid is injected under the skin directly into the area beneath your chin. A healthcare provider will give you this injection.

Deoxycholic acid must be given in a series of up to 6 treatment sessions in order to be effective. You may receive up to 50 injections at each session.

You may be treated with a topical numbing medicine or an ice pack to ease pain and make you comfortable during the injections.

Each treatment session should be spaced no less than 1 month apart. Many people have had visible results after 2 to 4 sessions.

Your doctor will determine the right number of injections and how many sessions you need, depending on the results you want.

What happens if I miss a dose?

Call your doctor for instructions if you miss an appointment for your deoxycholic acid injection.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid after receiving deoxycholic acid?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What are the possible side effects of deoxycholic acid?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • trouble swallowing;
  • weak muscles in your face; or
  • a crooked smile.

Common side effects may include:

  • pain, swelling, bruising, or redness of treated skin areas; or
  • numbness or hardening of treated areas.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect deoxycholic acid?

Tell your doctor about all your current medicines and any you start or stop using, especially:

  • a blood thinner --warfarin, Coumadin, Jantoven; or
  • any medicines to prevent blood clots.

This list is not complete. Other drugs may interact with deoxycholic acid, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

Where can I get more information?

Your doctor or pharmacist can provide more information about deoxycholic acid.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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