Scleroderma is a rare disease in which a person's immune system
begins to destroy normal, healthy tissues. (This is called an autoimmune disease.) As a result,
connective tissue of the skin, lungs, and internal organs-especially the
esophagus, kidneys, and digestive tract-is replaced with scar tissue. This
change causes the tissues to become stiff and the muscles to not work as
In the esophagus, this makes it:
CREST syndrome is a limited type of scleroderma that can also affect the esophagus.
ByHealthwise StaffPrimary Medical ReviewerAdam Husney, MD - Family MedicineMartin J. Gabica, MD - Family MedicineKathleen Romito, MD - Family MedicineSpecialist Medical ReviewerPeter J. Kahrilas, MD - Gastroenterology
Current as ofOctober 31, 2016
Current as of:
October 31, 2016
Adam Husney, MD - Family Medicine & Martin J. Gabica, MD - Family Medicine & Kathleen Romito, MD - Family Medicine & Peter J. Kahrilas, MD - Gastroenterology
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Last modified on: 8 September 2017